Thimet Oligopeptidase 1 antibody (AA 51-150)

Catalog No. ABIN1386027

Product Details anti-Thimet Oligopeptidase 1 Antibody

Target: Thimet Oligopeptidase 1 (THOP1)

Binding Specificity: AA 51-150

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Thimet Oligopeptidase 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Thimet Oligopeptidase

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Thimet Oligopeptidase 1

Target: Thimet Oligopeptidase 1 (THOP1)

Alternative Name: THOP1/Thimet Oligopeptidase (THOP1 Products)

Synonyms: EP24.15 antibody, MEPD_HUMAN antibody, MP78 antibody, TOP antibody, AI131655 antibody, AI327041 antibody, THOP1 antibody, thop1 antibody, MGC147297 antibody, LOC397806 antibody, mepd antibody, thimet oligopeptidase 1 antibody, thimet oligopeptidase 1 L homeolog antibody, thimet oligopeptidase antibody, peptidase antibody, Thimet oligopeptidase antibody, THOP1 antibody, Thop1 antibody, thop1 antibody, thop1.L antibody, Tc00.1047053506411.10 antibody, Tc00.1047053511237.10 antibody, Noca_4613 antibody, ANI_1_1400064 antibody, MBOO_RS10705 antibody, AOR_1_880174 antibody, AnaeK_0425 antibody, MPAL_RS03920 antibody, Hoch_5061 antibody, mepd antibody

Background:

Synonyms: Endopeptidase 24.15, EP24.15, MEPD_HUMAN, MP78, Thimet oligopeptidase 1, Thimet oligopeptidase, Thop1, THOP1_HUMAN, EC 3.4.24.15.

Background: Thimet oligopeptidase, also designated soluble metallo-endopeptidase, is a cytoplasmic protein belonging to the peptidase M3 family. The gene for the protein maps against chromosome 19q13.3. Thimet oligopeptidase can degrade the b-Amyloid precursor protein and generate amyloidogenic fragments. It is important in cytoplasmic peptide degradation and involved in metabolism of neuropeptides that are less than 20 amino acids in length. Thimet oligopeptidase is highly expressed in testis but can also be detected in liver, lung and kidney.