Thimet Oligopeptidase 1 antibody

Catalog No. ABIN7231786

The Rabbit Polyclonal anti-Thimet Oligopeptidase 1 antibody (ABIN7231786) specifically detects Thimet Oligopeptidase 1 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Thimet Oligopeptidase 1 antibody (ABIN7231786)

Target: Thimet Oligopeptidase 1 (THOP1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Thimet Oligopeptidase 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Thimet Oligopeptidase 1 Antibody

Purpose: Rabbit Anti-THOP1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of THOP1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human THOP1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Thimet Oligopeptidase 1

Target: Thimet Oligopeptidase 1 (THOP1)

Alternative Name: THOP1

Background: Thimet oligopeptidase, Endopeptidase 24.15, MP78Thimet Oligopeptidase 1 encoded by THOP1 is a kininase that uses zinc as a cofactor. The encoded oligopeptidase cleaves cytosolic peptides, making them unavailable for display on antigen-presenting cells. Thimet Oligopeptidase 1 also cleaves neuropeptides under 20 aa in length and can degrade beta-amyloid precursor protein to amyloidogenic peptides. THOP1 (Thimet Oligopeptidase 1) is a Protein Coding gene. Among its related pathways are African trypanosomiasis and ACE Inhibitor Pathway, Pharmacodynamics.

Molecular Weight: 75kD

Gene ID: 7064

UniProt: P52888