THO Complex 5 antibody (AA 530-610)

Catalog No. ABIN7225544

This Rabbit Polyclonal antibody specifically detects THO Complex 5 in ELISA, IHC, WB and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for THO Complex 5 antibody (AA 530-610) (ABIN7225544)

Target: THO Complex 5 (THOC5)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This THO Complex 5 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-THO Complex 5 Antibody

Binding Specificity: AA 530-610

Purpose: Rabbit Anti-FMIP Polyclonal Antibody

Specificity: FMIP Polyclonal Antibody detects endogenous levels of FMIP protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human FMIP at AA range: 530-610

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for THO Complex 5

Target: THO Complex 5 (THOC5)

Alternative Name: FMIP

Background: THOC5, C22orf19, KIAA0983, THO complex subunit 5 homolog, Functional spliceosome-associated protein 79, fSAP79, NF2/meningioma region protein pK1.3, Placental protein 39.2, PP39.2, hTREX90THOC5, also named as C22orf19, or KIAA0983, is a 683 amino acid protein, which belongs to the THOC5 family. THOC5 is ubiquitously expressed in many tissues. THOC5 localizes in the nucleus and acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. HOC5 plays a role in cytokine-stimulated monocytic development and affects granulocyte/macrophage differentiation.

Molecular Weight: 78kD

Gene ID: 8563

UniProt: Q13769