THNSL2 antibody (AA 91-140)

Catalog No. ABIN7231784

The Rabbit Polyclonal anti-THNSL2 antibody is suitable to detect THNSL2 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for THNSL2 antibody (AA 91-140) (ABIN7231784)

Target: THNSL2 (threonine Synthase-Like 2 (THNSL2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This THNSL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-THNSL2 Antibody

Binding Specificity: AA 91-140

Purpose: Rabbit Anti-THNS2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of THNS2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human THNS2 protein at AA range: 91-140

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for THNSL2

Target: THNSL2 (threonine Synthase-Like 2 (THNSL2))

Alternative Name: THNS2

Background: Threonine synthase-like 2, TSH2, Secreted osteoclastogenic factor of activated T-cells, SOFATTHNSL2 encodes a threonine synthase-like protein. A similar enzyme in mouse can catalyze the degradation of O-phospho-homoserine to a-ketobutyrate, phosphate, and ammonia. This protein also has phospho-lyase activity on both gamma and beta phosphorylated substrates. In mouse an alternatively spliced form of this protein has been shown to act as a cytokine and can induce the production of the inflammatory cytokine IL6 in osteoblasts. Alternate splicing results in multiple transcript variants.

Molecular Weight: 53kD

Gene ID: 55258

UniProt: Q86YJ6