THBS4 antibody (AA 551-600)

Catalog No. ABIN7231788

The Rabbit Polyclonal anti-THBS4 antibody is suitable to detect THBS4 in samples from Human, Mouse and Rat. It has been validated for IHC, ELISA and IF.

Quick Overview for THBS4 antibody (AA 551-600) (ABIN7231788)

Target: THBS4 (Thrombospondin 4 (THBS4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This THBS4 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-THBS4 Antibody

Binding Specificity: AA 551-600

Purpose: Rabbit Anti-Thrombospondin 4 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of Thrombospondin 4

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human Thrombospondin 4 protein at AA range: 551-600

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for THBS4

Target: THBS4 (Thrombospondin 4 (THBS4))

Alternative Name: Thrombospondin 4

Background: Thrombospondin-4The protein encoded by THBS4 belongs to the thrombospondin protein family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentamer and can bind to heparin and calcium. It is involved in local signaling in the developing and adult nervous system, and it contributes to spinal sensitization and neuropathic pain states. THBS4 is activated during the stromal response to invasive breast cancer. It may also play a role in inflammatory responses in Alzheimer's disease. Alternative splicing results in multiple transcript variants. THBS4 (Thrombospondin 4) is a Protein Coding gene. Diseases associated with THBS4 include Mycetoma and Myocardial Infarction. Among its related pathways are Focal Adhesion and PI3K-Akt signaling pathway.

Gene ID: 7060

UniProt: P35443