TSH receptor antibody (AA 280-360)

Catalog No. ABIN7231944

The Rabbit Polyclonal anti-TSH receptor antibody (ABIN7231944) specifically detects TSH receptor in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TSH receptor antibody (AA 280-360) (ABIN7231944)

Target: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSH receptor antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TSH receptor Antibody

Binding Specificity: AA 280-360

Purpose: Rabbit Anti-TSHR Polyclonal Antibody

Specificity: The antibody detects endogenous levels of TSHR protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human TSHR protein at AA range: 280-360

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TSH receptor

Target: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Alternative Name: TSHR

Background: Thyrotropin receptor, Thyroid-stimulating hormone receptor, TSH-RReceptor for the thyroid-stimulating hormone (TSH) or thyrotropin (PubMed: 11847099, PubMed: 12045258). Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2: GPHB5) or thyrostimulin (PubMed: 12045258). The activity of this receptor is mediated by G proteins which activate adenylate cyclase (PubMed: 11847099). Plays a central role in controlling thyroid cell metabolism (By similarity).

Molecular Weight: 84kD

Gene ID: 7253

UniProt: P16473

Pathways: Thyroid Hormone Synthesis