TSHB antibody

Catalog No. ABIN7231942

This Rabbit Polyclonal antibody specifically detects TSHB in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TSHB antibody (ABIN7231942)

Target: TSHB (Thyroid Stimulating Hormone, beta (TSHB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSHB antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TSHB Antibody

Purpose: Rabbit Anti-TSHB Polyclonal Antibody

Specificity: The antibody detects endogenous levels of TSHB protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human TSHB protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TSHB

Target: TSHB (Thyroid Stimulating Hormone, beta (TSHB))

Alternative Name: TSHB

Background: Thyroid-stimulating hormone subunit beta, Thyrotropin beta chain, INN: Thyrotropin alfaThe four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by TSHB is the beta subunit of thyroid stimulating hormone. Mutations in TSHB are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of TSHB results in multiple transcript variants.

Molecular Weight: 15kD

Gene ID: 7252

UniProt: P01222

Pathways: Thyroid Hormone Synthesis, Peptide Hormone Metabolism