KLF10/11 antibody (AA 360-440)

Catalog No. ABIN7224702

The Rabbit Polyclonal anti-KLF10/11 antibody is suitable to detect KLF10/11 in samples from Human, Mouse and Rat. It has been validated for IHC, ELISA and IF.

Quick Overview for KLF10/11 antibody (AA 360-440) (ABIN7224702)

Target: KLF10/11 (Kruppel-Like Factor 10/11 (KLF10/11))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLF10/11 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-KLF10/11 Antibody

Binding Specificity: AA 360-440

Purpose: Rabbit Anti-TIEG-1/2 Polyclonal Antibody

Specificity: TIEG-1/2 Polyclonal Antibody detects endogenous levels of TIEG-1/2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human TIEG-1/2 at AA range: 360-440

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for KLF10/11

Target: KLF10/11 (Kruppel-Like Factor 10/11 (KLF10/11))

Alternative Name: TIEG-1/2

Background: KLF10, TIEG, TIEG1, Krueppel-like factor 10, EGR-alpha, Transforming growth factor-beta-inducible early growth response protein 1, TGFB-inducible early growth response protein 1, TIEG-1, KLF11, FKLF, TIEG2, Krueppel-like factor 11, TransforKLF10 (Kruppel like factor 10) encodes a member of a family of proteins that feature C2H2-type zinc finger domains. The encoded protein is a transcriptional repressor that acts as an effector of transforming growth factor beta signaling. Activity of this protein may inhibit the growth of cancers, particularly pancreatic cancer. Alternative splicing results in multiple transcript variants.

Gene ID: 7071, 8462

UniProt: Q13118, O14901