TM2D1 antibody

Catalog No. ABIN7231836

The Rabbit Polyclonal anti-TM2D1 antibody (ABIN7231836) specifically detects TM2D1 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for TM2D1 antibody (ABIN7231836)

Target: TM2D1 (TM2 Domain Containing 1 (TM2D1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TM2D1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TM2D1 Antibody

Purpose: Rabbit Anti-TM2D1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of TM2D1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human TM2D1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TM2D1

Target: TM2D1 (TM2 Domain Containing 1 (TM2D1))

Alternative Name: TM2D1

Background: TM2 domain-containing protein 1, Amyloid-beta-binding protein, hBBPThe protein encoded by TM2D1 is a beta-amyloid peptide-binding protein. It contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily and known to be important in heterotrimeric G protein activation. Beta-amyloid peptide has been established to be a causative factor in neuron death and the consequent diminution of cognitive abilities observed in Alzheimer's disease. This protein may be a target of neurotoxic beta-amyloid peptide, and may mediate cellular vulnerability to beta-amyloid peptide toxicity through a G protein-regulated program of cell death. Several transcript variants have been found for TM2D1.

Molecular Weight: 22kD

Gene ID: 83941

UniProt: Q9BX74