TNIP2 antibody (AA 61-110)

Catalog No. ABIN7227160

This Rabbit Polyclonal antibody specifically detects TNIP2 in ELISA and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TNIP2 antibody (AA 61-110) (ABIN7227160)

Target: TNIP2 (TNFAIP3 Interacting Protein 2 (TNIP2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNIP2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TNIP2 Antibody

Binding Specificity: AA 61-110

Purpose: Abin-2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of Abin-2

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human Abin-2 protein at AA range: 61-110

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200), ELISA (1:10000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for TNIP2

Target: TNIP2 (TNFAIP3 Interacting Protein 2 (TNIP2))

Alternative Name: Abin-2

Background: Rabbit Anti-Abin-2 Polyclonal Antibody,TNFAIP3-interacting protein 2, A20-binding inhibitor of NF-kappa-B activation 2, ABIN-2, Fetal liver LKB1-interacting protein,TNIP2 encodes a protein which acts as an inhibitor of NFkappaB activation. The encoded protein is also involved in MAP/ERK signaling pathway in specific cell types. It may be involved in apoptosis of endothelial cells. Alternative splicing results in multiple transcript variants. A pseudogene related to TNIP2 is located on the X chromosome TNIP2 (TNFAIP3 Interacting Protein 2) is a Protein Coding gene. Among its related pathways are Ovarian tumor domain proteases and Activated TLR4 signalling.,Abin-2

Gene ID: 79155

UniProt: Q8NFZ5

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin