TLK1 antibody (AA 180-260)

Catalog No. ABIN7217334

The Rabbit Polyclonal anti-TLK1 antibody is suitable to detect TLK1 in samples from Human and Mouse. It has been validated for WB, ELISA and IHC.

Quick Overview for TLK1 antibody (AA 180-260) (ABIN7217334)

Target: TLK1 (Tousled-Like Kinase 1 (TLK1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-TLK1 Antibody

Binding Specificity: AA 180-260

Purpose: Rabbit Anti-TLK1 Polyclonal Antibody

Specificity: TLK1 Polyclonal Antibody detects endogenous levels of TLK1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human TLK1 at AA range: 180-260

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TLK1

Target: TLK1 (Tousled-Like Kinase 1 (TLK1))

Alternative Name: TLK1

Background: TLK1, KIAA0137, Serine/threonine-protein kinase tousled-like 1, PKU-beta, Tousled-like kinase 1Serine/threonine-protein kinase tousled-like 1 encoded by TLK1 is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 87kD

Gene ID: 9874

UniProt: Q9UKI8