TLK1 antibody

Catalog No. ABIN7226128

The Rabbit Polyclonal anti-TLK1 antibody (ABIN7226128) specifically detects TLK1 in ELISA and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for TLK1 antibody (ABIN7226128)

Target: TLK1 (Tousled-Like Kinase 1 (TLK1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLK1 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Product Details anti-TLK1 Antibody

Purpose: Rabbit Anti-TLK1 Polyclonal Antibody

Specificity: TLK1 Polyclonal Antibody detects endogenous levels of TLK1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human TLK1 around the non-phosphorylation site of S764

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF 1:200-1:1000,ELISA 1:5000,Not yet tested in other applications,

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TLK1

Target: TLK1 (Tousled-Like Kinase 1 (TLK1))

Alternative Name: TLK1

Background: TLK1, KIAA0137, Serine/threonine-protein kinase tousled-like 1, PKU-beta, Tousled-like kinase 1The protein encoded by TLK1 (tousled like kinase 1) is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for TLK1.

Gene ID: 9874

UniProt: Q9Y4F6