TRRAP antibody

Catalog No. ABIN7231932

The Rabbit Polyclonal anti-TRRAP antibody is suitable to detect TRRAP in samples from Human and Mouse. It has been validated for IHC and IF.

Quick Overview for TRRAP antibody (ABIN7231932)

Target: TRRAP (Transformation/transcription Domain-Associated Protein (TRRAP))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRRAP antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-TRRAP Antibody

Purpose: Rabbit Anti-TRRAP Polyclonal Antibody

Specificity: The antibody detects endogenous levels of TRRAP protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human TRRAP protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TRRAP

Target: TRRAP (Transformation/transcription Domain-Associated Protein (TRRAP))

Alternative Name: TRRAP

Background: Transformation/transcription domain-associated protein, 350/400 kDa PCAF-associated factor, PAF350/400, STAF40, Tra1 homologTRRAP (Transformation/Transcription Domain Associated Protein) encodes a large multidomain protein of the phosphoinositide 3-kinase-related kinases (PIKK) family. The encoded protein is a common component of many histone acetyltransferase (HAT) complexes and plays a role in transcription and DNA repair by recruiting HAT complexes to chromatin. Deregulation of TRRAP may play a role in several types of cancer including glioblastoma multiforme. Alternatively spliced transcript variants encoding multiple isoforms have been observed for TRRAP.

Molecular Weight: 424kD

Gene ID: 8295

UniProt: Q9Y4A5