TMEM185A antibody (AA 260-340)

Catalog No. ABIN7225424

The Rabbit Polyclonal anti-TMEM185A antibody (ABIN7225424) specifically detects TMEM185A in WB, ELISA, IF and IHC. The antibody is reactive with Human and Mouse samples.

Quick Overview for TMEM185A antibody (AA 260-340) (ABIN7225424)

Target: TMEM185A (Transmembrane Protein 185A (TMEM185A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM185A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-TMEM185A Antibody

Binding Specificity: AA 260-340

Purpose: Rabbit Anti-TMEM185A Polyclonal Antibody

Specificity: TMEM185A Polyclonal Antibody detects endogenous levels of TMEM185A protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human TMEM185A at AA range: 260-340

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TMEM185A

Target: TMEM185A (Transmembrane Protein 185A (TMEM185A))

Alternative Name: TMEM185A

Background: TMEM185A, CXorf13, FAM11A, Transmembrane protein 185A, Protein FAM11AThe protein encoded by TMEM185A (transmembrane protein 185A) is predicted to be a transmembrane protein. TMEM185A is best known for localizing to the CpG island of the fragile site FRAXF. The 5' untranslated region of this gene contains a CGG trinucleotide repeat sequence that normally consists of 7-40 tandem CGG repeats but which can expand to greater than 300 repeats. Methylation of the CpG island leads to transcriptional silencing of this gene, but neither the silencing nor an expanded repeat region appear to manifest itself in a clear phenotypic manner. Alternative splicing results in multiple transcript variants. A pseudogene of TMEM185A has been defined on the X chromosome.

Molecular Weight: 41kD

Gene ID: 84548

UniProt: Q8NFB2