TFF1 antibody (AA 10-50)

Catalog No. ABIN7230808

This Rabbit Polyclonal antibody specifically detects TFF1 in IHC, IF and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TFF1 antibody (AA 10-50) (ABIN7230808)

Target: TFF1 (Trefoil Factor 1 (TFF1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFF1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Product Details anti-TFF1 Antibody

Binding Specificity: AA 10-50

Purpose: Rabbit Anti-pS2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of pS2

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human pS2 protein at AA range: 10-50

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TFF1

Target: TFF1 (Trefoil Factor 1 (TFF1))

Alternative Name: pS2

Background: Trefoil factor 1, Breast cancer estrogen-inducible protein, PNR-2, Polypeptide P1.A, hP1.A, Protein pS2Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. Aliases, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. Aliase and two other related trefoil family member genes are found in a cluster on chromosome 21.

Gene ID: 7031

UniProt: P04155

Pathways: EGFR Signaling Pathway