CD300LB antibody (AA 61-110)

Catalog No. ABIN7227738

The Rabbit Polyclonal anti-CD300LB antibody (ABIN7227738) specifically detects CD300LB in ELISA, IHC and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for CD300LB antibody (AA 61-110) (ABIN7227738)

Target: CD300LB (TREM5) (Triggering Receptor Expressed On Myeloid Cells 5 (TREM5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD300LB antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CD300LB Antibody

Binding Specificity: AA 61-110

Purpose: Rabbit Anti-CD300b Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CD300b

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CD300b protein at AA range: 61-110

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CD300LB

Target: CD300LB (TREM5) (Triggering Receptor Expressed On Myeloid Cells 5 (TREM5))

Alternative Name: CD300b

Background: CMRF35-like molecule 7, CLM-7, CD300 antigen-like family member B, CMRF35-A2, Immune receptor expressed on myeloid cells 3, IREM-3, Leukocyte mono-Ig-like receptor 5, Triggering receptor expressed on myeloid cells 5, TREM-5, CD antigen CD300bCD300LB is a nonclassical activating receptor of the immunoglobulin (Ig) superfamily expressed on myeloid cells (Martinez-Barriocanal and Sayos, 2006 [PubMed 16920917]) Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitment of GRB2.

Gene ID: 124599

UniProt: A8K4G0