The Rabbit Polyclonal anti-TSEN54 antibody is suitable to detect TSEN54 in samples from Human and Mouse. It has been validated for WB, ELISA, IHC and IF.
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Expiry Date
12 months
Target
TSEN54
(tRNA Splicing Endonuclease 54 (TSEN54))
Alternative Name
TSEN54
Background
TSEN54, SEN54, tRNA-splicing endonuclease subunit Sen54, SEN54 homolog, HsSEN54, tRNA-intron endonuclease Sen54TSEN54 encodes a subunit of the tRNA splicing endonuclease complex, which catalyzes the removal of introns from precursor tRNAs. The complex is also implicated in pre-mRNA 3-prime end processing. Mutations in this gene result in pontocerebellar hypoplasia type 2.