TPSD1 antibody (AA 51-100)

Catalog No. ABIN7226870

The Rabbit Polyclonal anti-TPSD1 antibody (ABIN7226870) specifically detects TPSD1 in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for TPSD1 antibody (AA 51-100) (ABIN7226870)

Target: TPSD1 (Tryptase delta 1 (TPSD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPSD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TPSD1 Antibody

Binding Specificity: AA 51-100

Purpose: Rabbit Anti-Tryptase-3 Polyclonal Antibody

Specificity: Tryptase-3 Polyclonal Antibody detects endogenous levels of Tryptase-3.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from Tryptase-3 at AA range: 51-100

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TPSD1

Target: TPSD1 (Tryptase delta 1 (TPSD1))

Alternative Name: Tryptase-3

Background: Tryptase delta , Delta-tryptase, H mMCP-3-like tryptase III, Mast cell mMCP-7-like, Tryptase-3Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. Although TPSD1 (tryptase delta 1) may be an exception, most of the tryptase genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. TPSD1 was once considered to be a pseudogene, although it is now believed to be a functional gene that encodes a protein.

Molecular Weight: 26kD

Gene ID: 23430

UniProt: Q9BZJ3