Tryptophan Hydroxylase 2 antibody (pSer19)

Catalog No. ABIN7219418

The Rabbit Polyclonal anti-Tryptophan Hydroxylase 2 antibody has been validated for WB and ELISA. It is suitable to detect Tryptophan Hydroxylase 2 in samples from Human, Mouse and Rat.

Quick Overview for Tryptophan Hydroxylase 2 antibody (pSer19) (ABIN7219418)

Target: Tryptophan Hydroxylase 2 (TPH2)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tryptophan Hydroxylase 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Tryptophan Hydroxylase 2 Antibody

Binding Specificity: pSer19

Purpose: TPH2 (phospho Ser19) Polyclonal Antibody

Specificity: Phospho-TPH2 (S19) Polyclonal Antibody detects endogenous levels of TPH2 protein only when phosphorylated at S19.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human TPH2 Phospho-Ser19

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Tryptophan Hydroxylase 2

Target: Tryptophan Hydroxylase 2 (TPH2)

Alternative Name: TPH2

Background: Rabbit Anti-TPH2 (phospho Ser19) Polyclonal Antibody,TPH2, NTPH, Tryptophan 5-hydroxylase 2, Neuronal tryptophan hydroxylase, Tryptophan 5-monooxygenase 2,TPH2 encodes a member of the pterin-dependent aromatic acid hydroxylase family. The tryptophan hydroxylase 2 catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.,Tryptophan 5-hydroxylase 2

Molecular Weight: observerd band 56kDa

Gene ID: 121278

UniProt: Q8IWU9