TSC22D1 antibody (AA 40-120)

Catalog No. ABIN7225682

The Rabbit Polyclonal anti-TSC22D1 antibody is suitable to detect TSC22D1 in samples from Human, Rat and Mouse. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for TSC22D1 antibody (AA 40-120) (ABIN7225682)

Target: TSC22D1 (TSC22 Domain Family, Member 1 (TSC22D1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSC22D1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-TSC22D1 Antibody

Binding Specificity: AA 40-120

Purpose: Rabbit Anti-TSC-22 Polyclonal Antibody

Specificity: TSC-22 Polyclonal Antibody detects endogenous levels of TSC-22 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human TSC-22 at AA range: 40-120

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TSC22D1

Target: TSC22D1 (TSC22 Domain Family, Member 1 (TSC22D1))

Alternative Name: TSC-22

Background: TSC22D1, KIAA1994, TGFB1I4, TSC22, hucep-2, TSC22 domain family protein 1, Cerebral protein 2, Regulatory protein TSC-22, TGFB-stimulated clone 22 homolog, Transforming growth factor beta-1-induced transcript 4 proteinTSC22D1 (TSC22 domain family member 1) encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of TSC22D1 has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for TSC22D1.

Molecular Weight: 16kD

Gene ID: 8848

UniProt: Q15714