TSC1 antibody (AA 360-440)

Catalog No. ABIN7226840

The Rabbit Polyclonal anti-TSC1 antibody has been validated for ELISA and WB. It is suitable to detect TSC1 in samples from Human.

Quick Overview for TSC1 antibody (AA 360-440) (ABIN7226840)

Target: TSC1 (Tuberous Sclerosis 1 (TSC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSC1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-TSC1 Antibody

Binding Specificity: AA 360-440

Purpose: Hamartin Polyclonal Antibody

Specificity: Hamartin Polyclonal Antibody detects endogenous levels of Hamartin.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from Hamartin at AA range: 360-440

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for TSC1

Target: TSC1 (Tuberous Sclerosis 1 (TSC1))

Alternative Name: Hamartin

Background: Rabbit Anti-Hamartin Polyclonal Antibody,tuberous sclerosis 1,TSC1 (tuberous sclerosis 1) encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in TSC1 have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants.,Hamartin

Molecular Weight: observerd band 130kDa

Gene ID: 7248

UniProt: Q92574

Pathways: RTK Signaling, AMPK Signaling, Regulation of Cell Size, Tube Formation