TUBB1 antibody

Catalog No. ABIN7211924

The Mouse Monoclonal anti-TUBB1 antibody (ABIN7211924) specifically detects TUBB1 in WB, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TUBB1 antibody (ABIN7211924)

Target: TUBB1 (Tubulin, beta 1 (TUBB1))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This TUBB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-TUBB1 Antibody

Purpose: Mouse Anti-β I tubulin Monoclonal Antibody

Specificity: The antibody detects endgenousβ I tubulin proteins.

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Immunogen: Synthetic Peptide

Isotype: IgG1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-10000,IF 1:200,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.5 % BSA, 0.02 % sodium azide as Preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TUBB1

Target: TUBB1 (Tubulin, beta 1 (TUBB1))

Alternative Name: beta I tubulin

Background: TUBB1, Tubulin beta-1 chain, TUBB2A, TUBB2, Tubulin beta-2A chain, TUBB2B, Tubulin beta-2B chain, TUBB4B, TUBB2C, Tubulin beta-4B chain, Tubulin beta-2 chain, Tubulin beta-2C chain, TUBB3, TUBB4, Tubulin beta-3 chain, Tubulin beta-4 chain, Tubulin beta-IITUBB1 encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. tubulin beta 1 class VI is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in TUBB1 is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of tTUBB1 are found on chromosome Y.

Molecular Weight: 50kD

Gene ID: 81027

UniProt: Q9H4B7

Pathways: Microtubule Dynamics