UBASH3A antibody (AA 280-360)

Catalog No. ABIN7223176

The Rabbit Polyclonal anti-UBASH3A antibody (ABIN7223176) specifically detects UBASH3A in ELISA and WB. The antibody is reactive with Human and Mouse samples.

Quick Overview for UBASH3A antibody (AA 280-360) (ABIN7223176)

Target: UBASH3A (Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBASH3A antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-UBASH3A Antibody

Binding Specificity: AA 280-360

Purpose: Rabbit Anti-TULA Polyclonal Antibody

Specificity: TULA Polyclonal Antibody detects endogenous levels of TULA protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human TULA at AA range: 280-360

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:5000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for UBASH3A

Target: UBASH3A (Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A))

Alternative Name: TULA

Background: UBASH3A, STS2, Ubiquitin-associated and SH3 domain-containing protein A, Cbl-interacting protein 4, CLIP4, Suppressor of T-cell receptor signaling 2, STS-2, T-cell ubiquitin ligand 1, TULA-1UBASH3A (ubiquitin associated and SH3 domain containing A) encodes one of two family members belonging to the T-cell ubiquitin ligand (TULA) family. Both family members can negatively regulate T-cell signaling. This family member can facilitate growth factor withdrawal-induced apoptosis in T cells, which may occur via its interaction with AIF, an apoptosis-inducing factor. Alternative splicing of UBASH3A results in multiple transcript variants.

Molecular Weight: 75kD

Gene ID: 53347

UniProt: P57075