USP36 antibody (AA 470-550)

Catalog No. ABIN7223810

This Rabbit Polyclonal antibody specifically detects USP36 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for USP36 antibody (AA 470-550) (ABIN7223810)

Target: USP36 (Ubiquitin Specific Peptidase 36 (USP36))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP36 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-USP36 Antibody

Binding Specificity: AA 470-550

Purpose: Rabbit Anti-USP36 Polyclonal Antibody

Specificity: USP36 Polyclonal Antibody detects endogenous levels of USP36 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human USP36 at AA range: 470-550

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for USP36

Target: USP36 (Ubiquitin Specific Peptidase 36 (USP36))

Alternative Name: USP36

Background: USP36, KIAA1453, Ubiquitin carboxyl-terminal hydrolase 36, Deubiquitinating enzyme 36, Ubiquitin thioesterase 36, Ubiquitin-specific-processing protease 36USP36 (ubiquitin specific peptidase 36) encodes a member of the peptidase C19 or ubiquitin-specific protease family of cysteine proteases. Members of this family remove ubiquitin molecules from polyubiquitinated proteins. The encoded protein may deubiquitinate and stabilize the transcription factor c-Myc, also known as MYC, an important oncoprotein known to be upregulated in most human cancers. The encoded protease may also regulate the activation of autophagy. USP36 exhibits elevated expression in some breast and lung cancers.

Molecular Weight: 125kD

Gene ID: 57602

UniProt: Q9P275