USP38 antibody (AA 520-600)

Catalog No. ABIN7217454

The Rabbit Polyclonal anti-USP38 antibody (ABIN7217454) specifically detects USP38 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for USP38 antibody (AA 520-600) (ABIN7217454)

Target: USP38 (Ubiquitin Specific Peptidase 38 (USP38))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP38 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-USP38 Antibody

Binding Specificity: AA 520-600

Purpose: Rabbit Anti-USP38 Polyclonal Antibody

Specificity: USP38 Polyclonal Antibody detects endogenous levels of USP38 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human USP38 at AA range: 520-600

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for USP38

Target: USP38 (Ubiquitin Specific Peptidase 38 (USP38))

Alternative Name: USP38

Background: USP38, KIAA1891, Ubiquitin carboxyl-terminal hydrolase 38, Deubiquitinating enzyme 38, HP43.8KD, Ubiquitin thioesterase 38, Ubiquitin-specific-processing protease 38The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. USP38 (ubiquitin specific peptidase 38), also known as HP43. KD, is a 1,042 amino acid deubiquitinating enzyme that participates in the Ub pathway. A member of the peptidase C19 family, the catalytic activity of USP38 involves a combination of the ubiquitin carboxyl-terminal thiolester and water to produce ubiquitin and a thiol. USP38 is highly expressed in skeletal muscle and adrenal gland.

Molecular Weight: 120kD

Gene ID: 84640

UniProt: Q8NB14