UBXN11 antibody (AA 100-180)

Catalog No. ABIN7225846

The Rabbit Polyclonal anti-UBXN11 antibody is suitable to detect UBXN11 in samples from Human, Mouse and Rat. It has been validated for ELISA, IHC, WB and IF.

Quick Overview for UBXN11 antibody (AA 100-180) (ABIN7225846)

Target: UBXN11 (UBX Domain Protein 11 (UBXN11))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBXN11 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-UBXN11 Antibody

Binding Specificity: AA 100-180

Purpose: Rabbit Anti-Socius Polyclonal Antibody

Specificity: Socius Polyclonal Antibody detects endogenous levels of Socius protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Socius at AA range: 100-180

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for UBXN11

Target: UBXN11 (UBX Domain Protein 11 (UBXN11))

Alternative Name: Socius

Background: UBXN11, SOC, UBXD5, PP2243, UBX domain-containing protein 11, Colorectal tumor-associated antigen COA-1, Socius, UBX domain-containing protein 5UBXN11 (UBX domain protein 11) encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-terminal region. It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation. It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity through upstream signaling pathways. The 3' coding sequence of UBXN11 contains a polymoprhic region of 24 nt tandem repeats. Several transcripts containing between 1. and five repeat units have been reported. Multiple transcript variants encoding different isoforms have been found for UBXN11.

Molecular Weight: 57kD

Gene ID: 91544

UniProt: Q5T124