ULBP1 antibody

Catalog No. ABIN7229876

The Rabbit Polyclonal anti-ULBP1 antibody is suitable to detect ULBP1 in samples from Human. It has been validated for ELISA and WB.

Quick Overview for ULBP1 antibody (ABIN7229876)

Target: ULBP1 (UL16 Binding Protein 1 (ULBP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ULBP1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-ULBP1 Antibody

Purpose: Rabbit Anti-N2DL1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of N2DL1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human N2DL1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ULBP1

Target: ULBP1 (UL16 Binding Protein 1 (ULBP1))

Alternative Name: N2DL1

Background: UL16-binding protein 1, ALCAN-beta, NKG2D ligand 1, N2DL-1, NKG2DL1, Retinoic acid early transcript 1IUL16 Binding Protein 1 encoded by ULBP1 is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 26kD

Gene ID: 80329

UniProt: Q9BZM6

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process