ULBP3 antibody

Catalog No. ABIN7229880

This Rabbit Polyclonal antibody specifically detects ULBP3 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for ULBP3 antibody (ABIN7229880)

Target: ULBP3 (UL16 Binding Protein 3 (ULBP3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ULBP3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ULBP3 Antibody

Purpose: Rabbit Anti-N2DL3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of N2DL3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human N2DL3 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ULBP3

Target: ULBP3 (UL16 Binding Protein 3 (ULBP3))

Alternative Name: N2DL3

Background: UL16-binding protein 3, ALCAN-gamma, NKG2D ligand 3, N2DL-3, NKG2DL3, Retinoic acid early transcript 1NUL16 Binding Protein 3 encoded by ULBP3 is one of several related ligands of the KLRK1/NKG2D receptor, which is found in primary NK cells. Binding of these ligands to the receptor activates several signal transduction pathways, including the JAK2, STAT5 and ERK pathways. The encoded protein is expressed solubly and on the surface of many tumor cells, making it potentially an important target for therapeutics.

Molecular Weight: 26kD

Gene ID: 79465

UniProt: Q9BZM4

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process