UBP1 antibody

Catalog No. ABIN7232010

The Rabbit Polyclonal anti-UBP1 antibody (ABIN7232010) specifically detects UBP1 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for UBP1 antibody (ABIN7232010)

Target: UBP1 (Upstream Binding Protein 1 (LBP-1a) (UBP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-UBP1 Antibody

Purpose: Rabbit Anti-UBP1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of UBP1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human UBP1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for UBP1

Target: UBP1 (Upstream Binding Protein 1 (LBP-1a) (UBP1))

Alternative Name: UBP1

Background: Ubiquitin carboxyl-terminal hydrolase 1, Deubiquitinating enzyme 1, hUBP, Ubiquitin thioesterase 1, Ubiquitin-specific-processing protease 1USP1 (Ubiquitin Specific Peptidase 1) is a Protein Coding gene. Diseases associated with USP1 include Fanconi Anemia, Complementation Group A. Among its related pathways are DNA Damage and Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template. USP1 encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. The protein specifically deubiquitinates a protein in the Fanconi anemia (FA) DNA repair pathway. Alternate transcriptional splice variants have been characterized.

Molecular Weight: 86kD

Gene ID: 7398

UniProt: O94782