Urotensin 2 antibody (Internal Region)

Catalog No. ABIN7217448

The Rabbit Polyclonal anti-Urotensin 2 antibody is suitable to detect Urotensin 2 in samples from Human and Monkey. It has been validated for WB and ELISA.

Quick Overview for Urotensin 2 antibody (Internal Region) (ABIN7217448)

Target: Urotensin 2 (UTS2)

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Urotensin 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Urotensin 2 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-Urotensin II Polyclonal Antibody

Specificity: Urotensin II Polyclonal Antibody detects endogenous levels of Urotensin II protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Urotensin II

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Urotensin 2

Target: Urotensin 2 (UTS2)

Alternative Name: Urotensin II

Background: UTS2, Urotensin-2, Urotensin II, U-II, UIIUTS2 encodes a mature peptide that is an active cyclic heptapeptide absolutely conserved from lamprey to human. The active peptide acts as a vasoconstrictor and is expressed only in brain tissue. Despite the gene family name similarity, this gene is not homologous to urocortin, a member of the sauvagine/corticotropin-releasing factor/urotensin I family. Most of the proprotein is cleaved to make the mature peptide. Transcript variants encoding different preproprotein isoforms have been described for this gene.

Molecular Weight: 14kD

Gene ID: 10911

UniProt: O95399

Pathways: Negative Regulation of Hormone Secretion