VTI1A antibody (AA 1-80)

Catalog No. ABIN7219712

This Rabbit Polyclonal antibody specifically detects VTI1A in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for VTI1A antibody (AA 1-80) (ABIN7219712)

Target: VTI1A (Vesicle Transport through Interaction with t-SNAREs 1A (VTI1A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VTI1A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-VTI1A Antibody

Binding Specificity: AA 1-80

Purpose: Rabbit Anti-v-SNARE Vti1a Polyclonal Antibody

Specificity: V-SNARE Vti1a Polyclonal Antibody detects endogenous levels of v-SNARE Vti1a protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human v-SNARE Vti1a at AA range: 1-80

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for VTI1A

Target: VTI1A (Vesicle Transport through Interaction with t-SNAREs 1A (VTI1A))

Alternative Name: v-SNARE Vti1a

Background: VTI1A, Vesicle transport through interaction with t-SNAREs homolog 1A, Vesicle transport v-SNARE protein Vti1-like 2, Vti1-rp2Vesicle transport through interaction with t-SNAREs homolog 1A encoded by VTI1A is a member of the family of soluble N-ethylmaleimide-sensitive fusion protein-attachment protein receptors (SNAREs) that function in intracellular trafficking. This family member is involved in vesicular transport between endosomes and the trans-Golgi network. It is a vesicle-associated SNARE (v-SNARE) that interacts with target membrane SNAREs (t-SNAREs). Polymorphisms in this gene have been associated with binocular function, and also with susceptibility to colorectal and lung cancers. A recurrent rearrangement has been found between this gene and the transcription factor 7-like 2 (TCF7L2) gene in colorectal cancers. Alternative splicing results in multiple transcript variants.

Molecular Weight: 23kD

Gene ID: 143187

UniProt: Q96AJ9