VPS35 antibody (AA 511-560)

Catalog No. ABIN7226892

The Rabbit Polyclonal anti-VPS35 antibody (ABIN7226892) specifically detects VPS35 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for VPS35 antibody (AA 511-560) (ABIN7226892)

Target: VPS35 (Vacuolar Protein Sorting 35 (VPS35))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPS35 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-VPS35 Antibody

Binding Specificity: AA 511-560

Purpose: Rabbit Anti-VPS35 Polyclonal Antibody

Specificity: VPS35 Polyclonal Antibody detects endogenous levels of VPS35.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from VPS35 at AA range: 511-560

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for VPS35

Target: VPS35 (Vacuolar Protein Sorting 35 (VPS35))

Alternative Name: VPS35

Background: Vacuolar protein sorting-associated protein 35, hVPS35, Maternal-embryonic 3, Vesicle protein sorting 35VPS35 (VPS35, retromer complex component) belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex.

Molecular Weight: 92kD

Gene ID: 55737

UniProt: Q96QK1