Vamp-1+2+3 (Internal Region) antibody

Catalog No. ABIN7224556

The Rabbit Polyclonal anti-Vamp-1+2+3 antibody (ABIN7224556) specifically detects Vamp-1+2+3 in WB, IHC, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Vamp-1+2+3 (Internal Region) antibody (ABIN7224556)

Target: Vamp-1+2+3

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details

Binding Specificity: Internal Region

Purpose: Rabbit Anti-VAMP-1/2/3 Polyclonal Antibody

Specificity: VAMP-1/2/3 Polyclonal Antibody detects endogenous levels of VAMP-1/2/3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human VAMP-1/2/3

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details

Target: Vamp-1+2+3

Alternative Name: VAMP-1/2/3

Background: VAMP1, SYB1, Vesicle-associated membrane protein 1, VAMP-1, Synaptobrevin-1, VAMP2, SYB2, Vesicle-associated membrane protein 2, VAMP-2, Synaptobrevin-2, VAMP3, SYB3, Vesicle-associated membrane protein 3, VAMP-3, Cellubrevin, CEB, SynaptobSynapotobrevins, syntaxins, and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by VAMP1 (vesicle associated membrane protein 1) is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Mutations in VAMP1 are associated with autosomal dominant spastic ataxia 1. Multiple alternative splice variants have been described, but the full-length nature of some variants has not been defined.

Molecular Weight: 13kD

Gene ID: 6843, 6844, 9341

UniProt: P23763, P63027, Q15836