VEGFB antibody (AA 60-140)
Quick Overview for VEGFB antibody (AA 60-140) (ABIN7217482)
Target
See all VEGFB AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 60-140
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Purpose
- VEGF-B Polyclonal Antibody
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Specificity
- VEGF-B Polyclonal Antibody detects endogenous levels of VEGF-B protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the Internal region of human VEGF-B at AA range: 60-140
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- VEGFB (Vascular Endothelial Growth Factor B (VEGFB))
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Alternative Name
- VEGF-B
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Background
- Rabbit Anti-VEGF-B Polyclonal Antibody,VEGFB, VRF, Vascular endothelial growth factor B, VEGF-B, VEGF-related factor, VRF,VEGFB encodes a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1). Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified.,Vascular endothelial growth factor B
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Molecular Weight
- observerd band 21kDa
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Gene ID
- 7423
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UniProt
- P49765
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Pathways
- RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
Target
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