Versican antibody (AA 510-590)

Catalog No. ABIN7219770

The Rabbit Polyclonal anti-Versican antibody (ABIN7219770) specifically detects Versican in WB, IHC, ELISA and IF. The antibody is reactive with Mouse, Human and Rat samples.

Quick Overview for Versican antibody (AA 510-590) (ABIN7219770)

Target: Versican (Vcan)

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Versican antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-Versican Antibody

Binding Specificity: AA 510-590

Purpose: Rabbit Anti-Versican Polyclonal Antibody

Specificity: Versican Polyclonal Antibody detects endogenous levels of Versican protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human Versican at AA range: 510-590

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Versican

Target: Versican (Vcan)

Alternative Name: Versican

Background: VCAN, CSPG2, Versican core protein, Chondroitin sulfate proteoglycan core protein 2, Chondroitin sulfate proteoglycan 2, Glial hyaluronate-binding protein, GHAP, Large fibroblast proteoglycan, PG-MVCAN is a member of the aggrecan/versican proteoglycan family. Versican core protein encoded is a large chondroitin sulfate proteoglycan and is a major component of the extracellular matrix. This protein is involved in cell adhesion, proliferation, proliferation, migration and angiogenesis and plays a central role in tissue morphogenesis and maintenance. Mutations in this gene are the cause of Wagner syndrome type 1. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene ID: 1462

UniProt: P13611

Pathways: Glycosaminoglycan Metabolic Process