WFDC1 antibody

Catalog No. ABIN7232140

The Rabbit Polyclonal anti-WFDC1 antibody (ABIN7232140) specifically detects WFDC1 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for WFDC1 antibody (ABIN7232140)

Target: WFDC1 (WAP Four-Disulfide Core Domain 1 (WFDC1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WFDC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-WFDC1 Antibody

Purpose: Rabbit Anti-WFDC1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of WFDC1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human WFDC1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for WFDC1

Target: WFDC1 (WAP Four-Disulfide Core Domain 1 (WFDC1))

Alternative Name: WFDC1

Background: WAP four-disulfide core domain protein 1, Prostate stromal protein ps20, ps20 growth inhibitorWFDC1 (WAP Four-Disulfide Core Domain 1) is a Protein Coding gene. WFDC1 encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. WFDC1 is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. WFDC1 is downregulated in many cancer types and may be involved in the inhibition of cell proliferation. The encoded protein may also play a role in the susceptibility of certain CD4 memory T cells to human immunodeficiency virus infection. Alternative splicing results in multiple transcript variants.

Molecular Weight: 24kD

Gene ID: 58189

UniProt: Q9HC57