WDFY1 antibody

Catalog No. ABIN7232136

The Rabbit Polyclonal anti-WDFY1 antibody is suitable to detect WDFY1 in samples from Human and Mouse. It has been validated for ELISA and WB.

Quick Overview for WDFY1 antibody (ABIN7232136)

Target: WDFY1 (WD Repeat and FYVE Domain Containing 1 (WDFY1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDFY1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-WDFY1 Antibody

Purpose: Rabbit Anti-WDFY1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of WDFY1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human WDFY1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for WDFY1

Target: WDFY1 (WD Repeat and FYVE Domain Containing 1 (WDFY1))

Alternative Name: WDFY1

Background: WD repeat and FYVE domain-containing protein 1, FENS-1, Phosphoinositide-binding protein 1, WD40- and FYVE domain-containing protein 1, Zinc finger FYVE domain-containing protein 17Positively regulates TLR3- and TLR4-mediated signaling pathways by bridging the interaction between TLR3 or TLR4 and TICAM1. Promotes TLR3/4 ligand-induced activation of transcription factors IRF3 and NF-kappa-B, as well as the production of IFN-beta and inflammatory cytokines (PubMed: 25736436).

Molecular Weight: 45kD

Gene ID: 57590

UniProt: Q8IWB7