WNK4 antibody

Catalog No. ABIN7232152

This Rabbit Polyclonal antibody specifically detects WNK4 in ELISA and WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for WNK4 antibody (ABIN7232152)

Target: WNK4 (WNK Lysine Deficient Protein Kinase 4 (WNK4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WNK4 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-WNK4 Antibody

Purpose: Rabbit Anti-WNK4 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of WNK4 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human WNK4 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for WNK4

Target: WNK4 (WNK Lysine Deficient Protein Kinase 4 (WNK4))

Alternative Name: WNK4

Background: Serine/threonine-protein kinase WNK4, Protein kinase lysine-deficient 4, Protein kinase with no lysine 4WNK4 (WNK Lysine Deficient Protein Kinase 4) encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in WNK4 result in pseudohypoaldosteronism type IIB.

Molecular Weight: 136kD

Gene ID: 65266

UniProt: Q96J92