YTHDF1 antibody (AA 1-80)

Catalog No. ABIN7214506

This anti-YTHDF1 antibody is a Rabbit Polyclonal antibody detecting YTHDF1 in WB, ELISA and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for YTHDF1 antibody (AA 1-80) (ABIN7214506)

Target: YTHDF1 (YTH Domain Family, Member 1 (YTHDF1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YTHDF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-YTHDF1 Antibody

Binding Specificity: AA 1-80

Purpose: DACA-1 Polyclonal Antibody

Specificity: DACA-1 Polyclonal Antibody detects endogenous levels of DACA-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human DACA-1 at AA range: 1-80

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for YTHDF1

Target: YTHDF1 (YTH Domain Family, Member 1 (YTHDF1))

Alternative Name: DACA-1

Background: Rabbit Anti-DACA-1 Polyclonal Antibody,YTHDF1, C20orf21, YTH domain family protein 1, Dermatomyositis associated with cancer putative autoantigen 1, DACA-1,The YTH domain family protein family (YTHDF) includes YTHDF1, YTHDF2 and TYHDF3. YTHDF1, also designated Dermatomyositis associated with cancer putative autoantigen 1 (DACA-1), is a 559 amino acid protein that contains one YTH domain, which is a potential RNA binding domain. YTHDF2, also designated High-glucose-regulated protein 8, CLL-associated antigen KW-14 or Renal carcinoma antigen NY-REN-2, is a 579 amino acid protein that also contains one YTH domain. YTHDF3 is a 585 amino acid protein that also contains one YTH domain. The gene encoding YTHDF1 maps to chromosome 20, which houses over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception.,YTH domain family protein 1

Molecular Weight: observerd band 61kDa

Gene ID: 54915

UniProt: Q9BYJ9