YTHDF1 antibody (AA 1-80)

Catalog No. ABIN7214506

The Rabbit Polyclonal anti-YTHDF1 antibody (ABIN7214506) specifically detects YTHDF1 in WB, ELISA, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for YTHDF1 antibody (AA 1-80) (ABIN7214506)

Target: YTHDF1 (YTH Domain Family, Member 1 (YTHDF1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YTHDF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-YTHDF1 Antibody

Binding Specificity: AA 1-80

Purpose: Rabbit Anti-DACA-1 Polyclonal Antibody

Specificity: DACA-1 Polyclonal Antibody detects endogenous levels of DACA-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human DACA-1 at AA range: 1-80

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for YTHDF1

Target: YTHDF1 (YTH Domain Family, Member 1 (YTHDF1))

Alternative Name: DACA-1

Background: YTHDF1, C20orf21, YTH domain family protein 1, Dermatomyositis associated with cancer putative autoantigen 1, DACA-1The YTH domain family protein family (YTHDF) includes YTHDF1, YTHDF2 and TYHDF3. YTHDF1, also designated Dermatomyositis associated with cancer putative autoantigen 1 (DACA-1), is a 559 amino acid protein that contains one YTH domain, which is a potential RNA binding domain. YTHDF2, also designated High-glucose-regulated protein 8, CLL-associated antigen KW-14 or Renal carcinoma antigen NY-REN-2, is a 579 amino acid protein that also contains one YTH domain. YTHDF3 is a 585 amino acid protein that also contains one YTH domain. The gene encoding YTHDF1 maps to chromosome 20, which houses over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception.

Molecular Weight: 61kD

Gene ID: 54915

UniProt: Q9BYJ9