ZNRF2 antibody (AA 130-210)

Catalog No. ABIN7220506

This Rabbit Polyclonal antibody specifically detects ZNRF2 in ELISA, IHC and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for ZNRF2 antibody (AA 130-210) (ABIN7220506)

Target: ZNRF2 (Zinc and Ring Finger 2 (ZNRF2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNRF2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ZNRF2 Antibody

Binding Specificity: AA 130-210

Purpose: Rabbit Anti-ZNRF2 Polyclonal Antibody

Specificity: ZNRF2 Polyclonal Antibody detects endogenous levels of ZNRF2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human ZNRF2 at AA range: 130-210

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ZNRF2

Target: ZNRF2 (Zinc and Ring Finger 2 (ZNRF2))

Alternative Name: ZNRF2

Background: ZNRF2, RNF202, E3 ubiquitin-protein ligase ZNRF2, Protein Ells2, RING finger protein 202, Zinc/RING finger protein 2May play a role in the establisment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

Gene ID: 223082

UniProt: Q8NHG8

Pathways: Synaptic Membrane