ZNF420 antibody (AA 270-350)

Catalog No. ABIN7219794

This Rabbit Polyclonal antibody specifically detects ZNF420 in ELISA and WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for ZNF420 antibody (AA 270-350) (ABIN7219794)

Target: ZNF420 (Zinc Finger Protein 420 (ZNF420))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF420 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-ZNF420 Antibody

Binding Specificity: AA 270-350

Purpose: Rabbit Anti-ZNF420 Polyclonal Antibody

Specificity: ZNF420 Polyclonal Antibody detects endogenous levels of ZNF420 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human ZNF420 at AA range: 270-350

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ZNF420

Target: ZNF420 (Zinc Finger Protein 420 (ZNF420))

Alternative Name: ZNF420

Background: ZNF420, Zinc finger protein 420Zinc finger protein 420 encoded by ZNF420 is a KRAB-type zinc finger protein that negatively-regulates p53-mediated apoptosis. Under stress conditions, the encoded protein is phosphorylated by ATM and dissociates from p53, which activates p53 and initiates apoptosis.

Molecular Weight: 80kD

Gene ID: 147923

UniProt: Q8TAQ5