ZFYVE19 antibody (AA 280-360)

Catalog No. ABIN7217550

The Rabbit Polyclonal anti-ZFYVE19 antibody is suitable to detect ZFYVE19 in samples from Human and Mouse. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for ZFYVE19 antibody (AA 280-360) (ABIN7217550)

Target: ZFYVE19 (Zinc Finger, FYVE Domain Containing 19 (ZFYVE19))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZFYVE19 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ZFYVE19 Antibody

Binding Specificity: AA 280-360

Purpose: Rabbit Anti-ZFYVE19 Polyclonal Antibody

Specificity: ZFYVE19 Polyclonal Antibody detects endogenous levels of ZFYVE19 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human ZFYVE19 at AA range: 280-360

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ZFYVE19

Target: ZFYVE19 (Zinc Finger, FYVE Domain Containing 19 (ZFYVE19))

Alternative Name: ZFYVE19

Background: ZFYVE19, MPFYVE, Zinc finger FYVE domain-containing protein 19, MLL partner containing FYVE domainZinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZFYVE19 (zinc finger, FYVE domain containing 19), also known as MPFYVE (MLL partner containing FYVE domain), is a 471 amino acid protein that contains one FYVE-type zinc finger. Expressed in heart, brain, kidney, skeletal muscle and liver, ZFYVE19 may participate in transcriptional regulation events within the cell. Defects in the gene encoding ZFYVE19 are associated with acute myeloblastic leukemia (AML), a rapidly progressing cancer of the myeloid line of white blood cells that is characterized by fever, anemia, bone pain, shortness of breath and frequent infections. Three isoforms of ZFYVE19 exist due to alternative splicing events.

Molecular Weight: 50kD

Gene ID: 84936

UniProt: Q96K21