GABRD antibody (AA 15-34)

Catalog No. ABIN7233022

This Mouse Monoclonal antibody specifically detects GABRD in WB and IF/ICC. It exhibits reactivity toward Rat.

Quick Overview for GABRD antibody (AA 15-34) (ABIN7233022)

Target: GABRD (GABA A Receptor delta (GABRD))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This GABRD antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (fixed cells) (IF/ICC)

Clone: S151-3

Product Details anti-GABRD Antibody

Binding Specificity: AA 15-34

Purpose: Anti-δ GABA-A Receptor Mouse Monoclonal Antibody

Specificity: This antibody recognizes mouse and rat Delta GABA-A receptor.

Cross-Reactivity: Mouse, Rat

Purification: Purified by Protein G affinity chromatography.

Immunogen: Synthetic peptide corresponding to aa 15-34 of rat Delta GABA-A receptor (accession no. P18506).

Isotype: IgG2a

Application Details

Application Notes: Immunoblotting: use at 1-10 μg/mL. A band of ~55 kDa is detected.Immunohistochemistry and
Immunocytochemistry: use at 0.1-1 μg/mL
Immunofluorescence: use at 1-10 μg/mL
These are recommended concentrations. User should determine optimal concentrations for their application.
Positive control: Rat brain.

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Dilute in PBS or medium that is identical to that used in the assay system.

Concentration: Lot specific

Buffer: PBS, pH 7.4, 50 % glycerol, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: This antibody is stable for at least one (1) year at -20°C.

Target Details for GABRD

Target: GABRD (GABA A Receptor delta (GABRD))

Alternative Name: Gabrd

Background: γ-aminobutyric acid receptor subunit δ,GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.,GABA is the major inhibitory neuro- transmitter in the vertebrate brain. GABA receptors consist of five subunits that form a chloride ion channel. Subunit families alpha, beta, g, and delta have been studied extensively, e€ and epsilon have been identified recently. Studies of recombinant GABA receptors have shown that individual subunits and their subtypes confer different sensitivities to GABA receptor modulators. Subunit subtypes are differentially expressed throughout development and in different CNS regions, reducing the total number of possible isoforms that can be formed in different brain regions and in individual cells.,Cell junction, synapse, postsynaptic cell membrane, Multi-pass membrane protein. Cell membrane, Multi-pass membrane protein.,GABA(A receptor subunit δ

UniProt: P18506