ABHD12 antibody (AA 110-250)

Catalog No. ABIN7265355

The Rabbit Polyclonal anti-ABHD12 antibody (ABIN7265355) specifically detects ABHD12 in WB. The antibody is reactive with Human samples.

Quick Overview for ABHD12 antibody (AA 110-250) (ABIN7265355)

Target: ABHD12 (Abhydrolase Domain Containing 12 (ABHD12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABHD12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ABHD12 Antibody

Binding Specificity: AA 110-250

Purpose: ABHD12 Rabbit pAb

Sequence: YFIDLKKPQD QGLNHTCNYY LQPEEDVTIG VWHTVPAVWW KNAQGKDQMW YEDALASSHP IILYLHGNAG TRGGDHRVEL YKVLSSLGYH VVTFDYRGWG DSVGTPSERG MTYDALHVFD WIKARSGDNP VYIWGHSLGT G

Cross-Reactivity: Human, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 110-250 of human ABHD12 (NP_056415.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ABHD12

Target: ABHD12 (Abhydrolase Domain Containing 12 (ABHD12))

Alternative Name: ABHD12

Background: This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jan 2011],ABHD12A,BEM46L2,C20orf22,PHARC,dJ965G21.2,ABHD12,ABHD12

Gene ID: 26090

UniProt: Q8N2K0