ANP32E antibody (AA 1-70)

Catalog No. ABIN7265378

The Rabbit Polyclonal anti-ANP32E antibody is suitable to detect ANP32E in samples from Human. It has been validated for WB.

Quick Overview for ANP32E antibody (AA 1-70) (ABIN7265378)

Target: ANP32E (Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member E (ANP32E))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANP32E antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ANP32E Antibody

Binding Specificity: AA 1-70

Purpose: ANP32E Rabbit pAb

Sequence: MEMKKKINLE LRNRSPEEVT ELVLDNCLCV NGEIEGLNDT FKELEFLSMA NVELSSLARL PSLNKLRKLE

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human ANP32E (NP_112182.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ANP32E

Target: ANP32E (Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member E (ANP32E))

Alternative Name: ANP32E

Background: Histone chaperone that specifically mediates the genome-wide removal of histone H2A.Z/H2AZ1 from the nucleosome: removes H2A.Z/H2AZ1 from its normal sites of deposition, especially from enhancer and insulator regions. Not involved in deposition of H2A.Z/H2AZ1 in the nucleosome. May stabilize the evicted H2A.Z/H2AZ1-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state. Inhibits activity of protein phosphatase 2A (PP2A. Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis.,ANP32E,LANP-L,LANPL,Cell Biology & Developmental Biology,Apoptosis,Caspases,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Neuroscience,Cell Type Marker,ANP32E

Gene ID: 81611

UniProt: Q9BTT0