ADAM11 antibody (AA 290-430)

Catalog No. ABIN7265433

The Rabbit Polyclonal anti-ADAM11 antibody (ABIN7265433) specifically detects ADAM11 in WB and IF. The antibody is reactive with Human samples.

Quick Overview for ADAM11 antibody (AA 290-430) (ABIN7265433)

Target: ADAM11 (ADAM Metallopeptidase Domain 11 (ADAM11))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAM11 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-ADAM11 Antibody

Binding Specificity: AA 290-430

Purpose: ADAM11 Rabbit pAb

Sequence: METWADGDKI QVQDDLLETL ARLMVYRREG LPEPSDATHL FSGRTFQSTS SGAAYVGGIC SLSHGGGVNE YGNMGAMAVT LAQTLGQNLG MMWNKHRSSA GDCKCPDIWL GCIMEDTGFY LPRKFSRCSI DEYNQFLQEG G

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 290-430 of human ADAM11 (NP_002381.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ADAM11

Target: ADAM11 (ADAM Metallopeptidase Domain 11 (ADAM11))

Alternative Name: ADAM11

Background: This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded preproprotein is proteolytically processed to generate the mature protease. This gene represents a candidate tumor suppressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.,ADAM11,MDC,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,ADAM Protein Family,Ubiquitin,ADAM11

Molecular Weight: 57kDa/83kDa

Gene ID: 4185

UniProt: O75078