ANAPC2 antibody (AA 400-500)

Catalog No. ABIN7265581

This Rabbit Polyclonal antibody specifically detects ANAPC2 in WB. It exhibits reactivity toward Human.

Quick Overview for ANAPC2 antibody (AA 400-500) (ABIN7265581)

Target: ANAPC2 (Anaphase Promoting Complex Subunit 2 (ANAPC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANAPC2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ANAPC2 Antibody

Binding Specificity: AA 400-500

Purpose: ANAPC2 Rabbit pAb

Sequence: YISAIKALRV LDPSMVILEV ACEPIRRYLR TREDTVRQIV AGLTGDSDGT GDLAVELSKT DPASLETGQD SEDDSGEPED WVPDPVDADP GKSSSKRRSS D

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 400-500 of human ANAPC2 (NP_037498.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ANAPC2

Target: ANAPC2 (Anaphase Promoting Complex Subunit 2 (ANAPC2))

Alternative Name: ANAPC2

Background: A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation.,ANAPC2,APC2,Cell Biology & Developmental Biology,Cell Cycle,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,ANAPC2

Molecular Weight: 93kDa

Gene ID: 29882

UniProt: Q9UJX6

Pathways: Regulation of Cell Size