ANAPC2 antibody

Catalog No. ABIN7128400

Product Details anti-ANAPC2 Antibody

Target: ANAPC2 (Anaphase Promoting Complex Subunit 2 (ANAPC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANAPC2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse

Purification: Antigen affinity purification

Immunogen: Fusion protein of Human ANAPC2

Isotype: IgG

Application Details

Application Notes: ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:25-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ANAPC2

Target: ANAPC2 (Anaphase Promoting Complex Subunit 2 (ANAPC2))

Alternative Name: ANAPC2 (ANAPC2 Products)

Synonyms: anapc2 antibody, ANAPC2 antibody, DDBDRAFT_0203816 antibody, DDBDRAFT_0234264 antibody, DDB_0203816 antibody, DDB_0234264 antibody, si:ch73-203i15.5 antibody, APC2 antibody, RP11-350O14.5 antibody, 9230107K09Rik antibody, AL024279 antibody, Apc2 antibody, Emi4 antibody, Imi4 antibody, mKIAA1406 antibody, F28I8.30 antibody, F28I8_30 antibody, anaphase-promoting complex/cyclosome 2 antibody, anaphase promoting complex subunit 2 antibody, anaphase promoting complex subunit 2 L homeolog antibody, anaphase-promoting complex/cyclosome 2 antibody, Anaphase-promoting complex subunit 2 antibody, ANAPC2 antibody, anapc2.L antibody, anapc2 antibody, Anapc2 antibody, APC2 antibody, apc-2 antibody

Background:

Background: A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation.

Aliases: anapc2 antibody, Anaphase promoting complex subunit 2 antibody, Anaphase-promoting complex subunit 2 antibody, ANC2_HUMAN antibody, APC2 antibody, Cyclosome subunit 2 antibody, KIAA1406 antibody, OTTHUMP00000022692 antibody, RP11 350O14.5 antibody

UniProt: Q9UJX6

Pathways: Regulation of Cell Size