NADAP antibody (AA 401-500)

Catalog No. ABIN717056

The Rabbit Polyclonal anti-NADAP antibody is suitable to detect NADAP in samples from Human. It has been validated for WB, ELISA, IHC (p), IF (cc), IF (p) and IHC (fro).

Quick Overview for NADAP antibody (AA 401-500) (ABIN717056)

Target: NADAP (SLC4A1AP) (Solute Carrier Family 4 (Anion Exchanger), Member 1, Adaptor Protein (SLC4A1AP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NADAP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-NADAP Antibody

Binding Specificity: AA 401-500

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Kanadaptin

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for NADAP

Target: NADAP (SLC4A1AP) (Solute Carrier Family 4 (Anion Exchanger), Member 1, Adaptor Protein (SLC4A1AP))

Alternative Name: HLC3

Background:

Synonyms: HLC3, HLC-3, Human lung cancer oncogene 3 protein, Kanadaptin, Kidney anion exchanger adapter protein, Kidney anion exchanger adaptor protein, Lung cancer oncogene 3 protein, NADAP_HUMAN, SLC4A1AP, Solute carrier family 4 anion exchanger member 1 adaptor protein, Solute carrier family 4 anion exchanger member 1 adapter protein.

Background: HLC-3 is a 796 amino acid protein that is widely expressed in many tissues, including kidney, lung, liver, brain and skeletal and cardiac muscle. SLC4A1AP is a multidomain protein that localizes to the nucleus where it may play a role in signaling. SLC4A1AP was previously thought to act as an adaptor protein or chaperone involved in targeting kAE1 to the plasma membrane. However, recent studies suggest SLC4A1AP does not interact with kAE1. The gene encoding SLC4A1AP maps to chromosome 2, which consists of 237 million bases and makes up approximately 8 % of the human genome.

Gene ID: 22950